教育与工作经历

2006.09 - 2010.07                南开大学                               学士

2010.09 - 2013.07                南开大学                               硕士

2013.09 - 2016.07                南开大学                               博士

2016.07 - 2020.03                国家纳米科学中心               助理研究员

2020.03 - 至今                     国家纳米科学中心               副研究员

主要研究方向

基于核酸化学修饰与可控自组装的基因治疗

主持科研项目

国家自然科学基金面上及青年基金项目、中科院青促会会员人才项目

代表性论文

[1] T. Wu, Y. Cao, Q. Liu, X. Wu, Y. Shang, J. Piao, Y. Li, Y. Dong, D. Liu, H. Wang^*, J. Liu^*, B. Ding^*. Genetically encoded double-stranded DNA-based nanostructure folded by a covalently bivalent CRISPR/dCas system. Journal of the American Chemical Society 2022, 144(14), 6575-6582.

[2] Y. Li, J. Pei^*, X. Lu, Y. Jiao, F. Liu, X. Wu, J. Liu^*, B. Ding^*. Hierarchical assembly of super-DNA origami based on a flexible and covalent-bound branched DNA structure. Journal of the American Chemical Society 2021, 143(47), 19893-19900.

[3] J. Liu^*, X. Lu, T. Wu, X. Wu, L. Han, B. Ding^*. Branched antisense and siRNA co-assembled nanoplatform for combined gene silencing and tumor therapy. Angewandte Chemie International Edition 2021, 60(4), 1853-1860.

[4] J. Liu, T. Wu, X. Lu, X. Wu, S. Liu, S. Zhao, X. Xu, B. Ding. A self-assembled platform based on branched DNA for sgRNA/Cas9/antisense delivery. Journal of the American Chemical Society 2019, 141(48), 19032-19037.

[5] J. Liu, L. Song, S. Liu, S. Zhao, Q. Jiang, B. Ding. A tailored DNA nanoplatform for synergistic RNAi-/chemotherapy of multidrug-resistant tumors. Angewandte Chemie International Edition 2018, 57(47), 15486-15490.