季天骄，国家纳米科学中心研究员，博士生导师，国家级青年人才项目获得者，中国科学院大学双聘教授、岗位教师、小米青年学者，中国抗癌协会癌痛整合治疗专委会常委（唯一非临床代表），中国青年科协、北京市青年科协会员；2011年于武汉大学化学基地班专业获学士学位；2016年于中国科学院大学获博士学位，并获“2017年度中科院百篇优秀博士论文”奖项，导师为聂广军研究员；2016-2020年在哈佛医学院（HMS）波士顿儿童医院及麻省理工学院（MIT）进行博士后研究，合作导师为Daniel S. Kohane教授和Robert Langer教授；2020年9月加入国家纳米科学中心，组建“药物递送与疼痛管理”实验室；近年来，在Nat. Biomed. Eng., Cell Biomater., Nat. Commun., Adv. Mater., Angew. Chem. Int. Ed., Nano Today, Nano Lett., ACS Nano等期刊上发表论文70余篇；申请美国发明专利2项，中国发明专利14项, 已授权9项；获得“2020年度北京市科学技术奖（自然科学）一等奖”（排名：6/10）。

担任Nat. Nanotechnol. Sci. Adv., Adv. Mater., Nano Today, Nano Lett., ACS Nano, Biomaterials等期刊审稿人。当选英国化学会（The Royal Society of Chemistry）J. Mater. Chem. B期刊2020新锐科学家（2020 Emerging Investigators）。

（1）载体化学生物学

（2）药物递送与疼痛管理

（3）纳米技术与神经调控

课题组欢迎具有化学生物学、神经科学、药学等相关专业的学生、博士后、工作人员加入。

1. Zhang S, Liu Z, Ma X, Zu M, Wang M, Zheng W, Yang H, Ma H, Zhao R, Chen Z, Liu Y, Zhao J, Zong Y, Gao T, Yang D, Jiamin Miao J*, Chen H*, Nie G*, Ji T*. Nanoformulated oxaliplatin reduces platinum accumulation in dermal fibroblasts to alleviate cold allodynia. Cell Biomater. 2026, 10.1016/j.celbio.2026.100345.

2. Ma X, Liu S, Zhang S, Liu Z, Wang H, Luo W, Zu M, Qin H, Li Z, Zhong J, Li J, Chen Q, Lin J, Liu A, Zhang X, Li H, Lu X, Shi X, Li L*, Gu Z*, Nie G*, Ji T*. Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy. Nat. Commun. 2025, 16, 8913.

3. Liu Y, Wu Y, Zu M, Li X, Zhang J, Wang D, Ji T*, Miao J*. Transferrin-phosphatidylserine liposomes target TDP-43 and neuroinflammation in male mice with neuropathic pain. Nat. Commun. 2025 16, 11314.

4. Wang C, Zhang R, Jeong KJ, Xiong W, Liu Z, Xie Z, Hou L, Gong J, Lian Z*, Zu M*, Fan K*, Ji T*. Fabrication of a Whitlockite/PLGA Scaffold with Hierarchical Porosity for Bone Repair. Nano Lett. 2025, 25, 4386-4392.

5. Zhang L, Li Z, Wang F, Chen Q, Zu M, Li X, Wan J, Yao X, Lou X, Shi Y, Sheng Y, Wang M, Yang J, Wang X, Qin Z.*, Ji T*. Integrin-Enriched Membrane Nanocarrier for the Specific Delivery of RGD‐modified Relaxin Analog to Inhibit Pancreatic Cancer Liver Metastasis through Reversing Hepatic Stellate Cell Activation. Adv. Funct. Mater. 2022, 32, 2208404.

6. T. Ji, Y. Li, X. Deng, A. Y. Rwei, A. Offen, S. Hall, W. Zhang, C. Zhao, M. Mehta, D. S. Kohane*. Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel. Nat. Biomed. Eng. 2021, 5, 1099-1109.

7. Song S, Ma X, Li X, Xu B, Li W, Deng R, Ye J, Liu Z, Yu H, Xu L, Zhang S, Yang D, Zu M*, Ji T*, Nie G*, Yu JK*. Targeting a key pro-fibrotic factor S100A4 in cartilage to alleviate osteoarthritis progression and pain. Nano Today 2025, 63, 102755.

8. Zhu L, Zu M, Wu F, Ma X, Zhang S, Zhang T, Li X, Yang H, Li Z, Yu Z, Nie R, Ji T*, Zhang X*, Liu R*. Cancer-associated fibroblasts regulating nanomedicine to overcome sorafenib resistance in hepatocellular carcinoma with portal vein tumor thrombus. Biomaterials. 2026, 325, 123599.

9. Li C, Lang J, Wang Y, Cheng Z, Zu M, Li F, Sun J, Deng Y, Ji T*, Nie G*, Zhao Y*. Self-assembly of CXCR4 antagonist peptide-docetaxel conjugates for breast tumor multi-organ metastasis inhibition. Acta Pharm. Sin B. 2023, 13, 3849-3861.

10. Li M, He Y, Liu Z, Ma X, Sun F, Pei L, Ma C, Liu H, Ji T*, Huang Y*. Construction of meloxicam and bupivacaine co-delivery nanosystem based on the pathophysiological environment of surgical injuries for enhanced postoperative analgesia Nano Research 2023, 16, 13301-13308

11. Yu H, Zhang S, Yang H, Miao J, Ma X, Xiong W, Chen G*, Ji T*. Specific interaction based drug loading strategies. Nanoscale Horiz. 2023, 8, 1523-1528.

12. Wheeler TT, Cao P, Ghouri MD, Ji T*, Nie G, Zhao YL*. Nanotechnological strategies for prostate cancer imaging and diagnosis. Sci. China Chem. 2022, 65, 1498-1514.

13. Lang J, Zhao X, Qi Y, Zhang Y, Han X, Ding Y, Guan J, Ji T*, Zhao Y*, Nie G*. Reshaping Prostate Tumor Microenvironment to Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem. ACS Nano 2019, 13, 12357-12371.

14. T. Ji, J. Lang, B. Ning, F. Qi, H. Wang, Y. Zhang, R. Zhao, X. Yang, L. Zhang, W. Li, X. Shi, Z. Qin, Y. Zhao, G. Nie. Enhanced Natural Killer Cell Immunotherapy by Rationally Assembling Fc Fragments of Antibodies onto Tumor Membranes. Adv. Mater. 2019, 31, 1804395.

15. T. Ji, D. S. Kohane. Nanoscale systems for local drug delivery. Nano Today 2019, 28, 10765.

16. T. Ji, J. Lang, J. Wang, R. Cai, Y. Zhang, F. Qi, L. Zhang, X. Zhao, W. Wu, J. Hao, Z. Qin*, Y. Zhao*, G. Nie*. Designing Liposomes to Suppress Extracellular Matrix Expression to Enhance Drug Penetration and Pancreatic Tumor Therapy. ACS Nano 2017, 11, 8668-8678.

17. T. Ji, Y. Zhao, Y. Ding, J. Wang, R. Zhao, J. Lang, H. Qin, X. Liu, J. Shi, N. Tao, Z. Qin, G. Nie, YL. Zhao*. Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-associated Fibroblasts Activation. Angew. Chem. Int. Ed. 2016, 55, 1050-1055.

18. T. Ji, Y. Ding, Y. Zhao*, J. Wang, H. Qin, X. Liu, et al. Peptide Assemblies Integration of Fibroblast Targeting and Cell Penetration Features for Enhanced Antitumor Drugs Delivery. Adv. Mater. 2015, 27, 1865-1873.

19. T. Ji, Y. Zhao, Y. Ding, G. Nie*, Using Nanomaterials to Target and Regulate the Tumor Microenvironment: Diagnostic and Therapeutic Applications. Adv. Mater. 2013, 25, 3508-3525.

20. T. Ji, Y. Zhao, J. Wang, X. Zheng, Y. Tian, et al. Tumor Fibroblast Specific Activation of Hybrid Ferritin Nanocage-based Optical Probe for Tumor Microenvironment Imaging. Small 2013, 9, 2427-2431. 

课题组已获得多项国家自然科学基金委、国家重点研发计划、北京市重点专项、中国科学院人才支持项目等资助。