人才队伍

姓    名:
孟幻
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
mengh@nanoctr.cn

 简历:
 

孟幻,国家纳米科学中心研究员,博士生导师。孟幻研究员毕业于北京大学和中国科学院研究生院,获药学专业学士和生物无机化学专业博士学位。毕业后,赴美国加州大学洛杉矶分校(UCLA)从事科研工作十余年,回国前,在UCLA任副教授。孟幻研究员长期开展药物递送、纳米化学生物学和纳米安全性研究,先后在Accounts of Chemical Research、Nature Communications、PNAS、Nature Food、ACS Nano、JACS、Chem、Advanced Science、Journal of Clinical Investigation、Advanced Materials等学术期刊发表SCI论文120余篇,引用20000余次,h因子59,入选全球高引科学家。孟幻研究员入选中科院人才计划,是科技部重点研发计划首席科学家,现担任中国毒理学会副秘书长、纳米毒理专业委员会副主任委员、中国抗癌协会纳米肿瘤学专业委员会常务委员、《Nano Today》编辑等职。

课题组网站:www.meng-nanorxlab.com


 研究领域:
 


纳米生物界面、纳米化学生物学、纳米药物递送、纳米安全性。


 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 


l   Y Ji, X Liu, J Li, X Xie, M Huang, J Jiang Y-P Liao, T Donahue, H Meng*, Use of Ratiometrically Designed Nanocarrier Targeting CDK4/6 And Autophagy Pathways for Effective Pancreatic Cancer Treatment. Nature Communications, 2020, 11, 4249

l   M Qin, Z Feng, H Meng*, Targeting Metalloimmunology via a Nanoenabled Approach to Effectively Treating Solid Tumors, Chem, 2024, in press

l   J Li, X Liu, K Ma, Y Liu, H Meng*, Understanding of Surface Chemistry of Silica-Based Nanomaterials Contributes to The Design Of Safe And Efficacious Nanomedicine, Matter, 2023, 6, 2564-2567

l   J Li, X Gao, Y Wang, T Xia, Y Zhao, H Meng*; Precision Design of Engineered Nanomaterials to Guide Immune Systems for Disease Treatment, Matter, 2022, 5, 1162-1191

l   J Li, Y Xiao, Y Zhang, S Li, M Zhao, T Xia*, H Meng*, Pulmonary Delivery of Specialized Pro-Resolving Mediators-Based Nanotherapeutics Attenuates Pulmonary Fibrosis in Preclinical Animal Models, ACS Nano, 2023, 17, 15354-15370  

l   S Dong, Z Feng, R Ma, T Zhang, J Jiang, Y Li, Y Zhang, S Li, X Liu, X Liu*, H Meng*, Engineered Design of a Mesoporous Silica Nanoparticle-Based Nanocarrier for Efficient mRNA Delivery In Vivo, Nano Letters, 2023, 23, 2137-2147

l   W Xu, Y Xiao, M Zhao, J Zhu, Y Wang, W Wang, P Wang*, H Meng*, Effective Treatment of Knee Osteoarthritis Using a Nano-Enabled Drug Acupuncture Technology in Mice. Advanced Science, 2023, 10, 2302586

l   X Liu, X Xie, J Jiang, M Lin, E Zheng, W Qiu, I Yeung, M Zhu, Q Li, T Xia, H Meng*, Use of Nanoformulation to Target Macrophages for Disease Treatment, Advanced Functional Materials, 2021, 31, 2104487

l   X Xie, J Jiang, X Liu, Y Cao, J Li, T Xia, H Meng*, Interleukin-10 Plasmid Delivery by Polymeric Nanocarrier Shows Efficient And Safe Tissue Repair in Acute Muscle Damage Models in Mice, Nano Today, 2022,46, 101544

l   X Liu, I Tang, Z A, Wainberg, H Meng*, Safety Considerations of Cancer Nanomedicine A Key Step Towards Translation, Small, 2020, 2000673

l   X Liu, J Jiang, R Chan, Y Ji, J Lu, YP Liao, M Okene, J Lin, P Lin, CH Chang, X Wang, I Tang, E Zheng, W Qiu, ZA. Wainberg, A Nel,* and H Meng*, Improved Efficacy and Reduced Toxicity Using  a Custom-Designed Irinotecan-Delivering  Silicasome for Orthotopic Colon Cancer, ACS Nano, 2019, 13, 38-53

l   X Liu, P Lin, I Perrett, J Lin, Y Liao, CH Chang, J Jiang, N Wu, T Donahue, Z Wainberg, A Nel*,  H Meng*, Tumor-Penetrating Peptide Enhances Transcytosis of Silicasome-based Chemotherapy for Pancreatic Cancer, The Journal of Clinical Investigation, 2017, 127, 20072018

注:

* 全部论文共120余篇,IF大于10的60余篇

* 论文列表:https://scholar.google.com/citations?user=JSDANEQAAAAJ&hl=en



 承担科研项目情况: