人才队伍

姓    名:
王亚玲
性    别:
职    务:
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
wangyl@nanoctr.cn

 简历:
 

  王亚玲,国家纳米科学中心研究员,广州市新发传染病疫苗研发技术创新促进会理事。主要研究方向为基于先进光源的纳米生物分析方法、新型纳米佐剂、药物开发及产业化研究。近年来,在Acc. Chem. Res., ACS Cent. Sci., Nano Today, Angew. Chem. Int. Ed., Anal. Chem., ACS Nano,等期刊上等期刊上发表70余篇论文,申请发明专利18项,获授权国家发明专利3项。主持科研项目6项,包括作为首席科学家承担了科技部政府间科技合作重点专项,主持了国家重点研发计划大科学装置专项课题1项,国家自然科学基金青年、面上、重点项目课题各1项,作为项目骨干参加中科院先导B项目、纳米生物效应及分析方法等相关十多个项目研究。


 研究领域:
 

1.基于先进光源的新型探针及纳米生物创新分析方法;

2.新型纳米佐剂开发及产业化应用;

3.抗肿瘤纳米药物研究及治疗应用。


 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

1. Chunyu Zhang#; Kai Zhang#; Yanyan Cui#; Yuecong Guo; Chuan Wang; Chao Xu; Qingqiang Yao; Yuliang Zhao; Chunying Chen*; Yaling Wang*, Multifunctional Nanoprobe for 3D Nanoresolution Imaging of Intact Cell HER2 Protein with Hard X-ray Tomography. Anal. Chem. 2023, 95 (4), 2129-2133.

2. Ping Zhang; Yanyan Cui*; Yaling Wang*, Designing temporal- and spatial-control multifunctional nanoformulations for synergistic photodynamic–enhanced tumour immunotherapy. Nano Today 2023, 49, 101816.

3. Yaling Wang; Chunying Chen*, DNA nanostructure-enabled precise control over the intermembrane spacing between cells. Sci. Bull. 2023, 68 (9), 871-873.

4. Xi Chen; Susu Gao; Xin Wang; Mengyu Guo; Yanyan Cui; Ziwei Chen; Ying Liu; Yaling Wang*, Advances in the biological mechanism and application of manganese-based nanoformulations for enhanced immunotherapy. Nano Today 2022, 46, 101583.

5. Mingjing Cao; Kai Zhang; Shuhan Zhang; Yaling Wang*; Chunying Chen*, Advanced Light Source Analytical Techniques for Exploring the Biological Behavior and Fate of Nanomedicines. ACS Cent. Sci. 2022, 8 (8), 10631080.

6. Chunyu Zhang; Shengkun Yao; Chao Xu; Yanan Chang; Yunbing Zong; Kai Zhang; Xiangzhi Zhang; Lijuan Zhang; Chunying Chen; Yuliang Zhao; Huaidong Jiang*; Xueyun Gao*; Yaling Wang*, 3D Imaging and Quantification of the Integrin at a Single-Cell Base on a Multisignal Nanoprobe and Synchrotron Radiation Soft X-ray Tomography Microscopy. Anal. Chem. 2021, 93 (3), 1237-1241.

7. Yaling Wang#; Yuping Xie#; Jia Luo#; Mengyu Guo#; Xuhao Hu; Xi Chen; Ziwei Chen; Xinyi Lu; Lichun Mao; Kai Zhang; Liangnian Wei; Yunfei Ma; Ruixin Wang; Jia Zhou; Chunyan He; Yufang Zhang; Ye Zhang; Sisi Chen; Lijuan Shen; Yun Chen; Nasha Qiu; Ying Liu; Yanyan Cui; Guoyang Liao; Ye Liu*; Chunying Chen*, Engineering a self-navigated MnARK nanovaccine for inducing potent protective immunity against novel coronavirus. Nano Today 2021, 38, 101139.

8. Yanyan Cui*; Xi Chen; Yan Cheng; Xinyi Lu; Jiajia Meng; Ziwei Chen; Mengke Li; Chengcheng Lin; Yaling Wang*; Jian Yang*, CuWO4 Nanodots for NIR-Induced Photodynamic and Chemodynamic Synergistic Therapy. ACS Appl. Mater. Interfaces 2021, 13 (19), 22150-22158.

9. Zilong Zhao#; Yaling Wang#; Liping Qiu#; Ting Fu; Yu Yang; Ruizi Peng; Mengyu Guo; Lichun Mao; Chunying Chen*; Yuliang Zhao; Weihong Tan*, New Insights from Chemical Biology: Molecular Basis of Transmission, Diagnosis, and Therapy of SARS-CoV-2. CCS Chemistry 2020, 2, 1501-1528.

10. Yaling Wang; Rong Cai; Chunying Chen, The Nano–Bio Interactions of Nanomedicines: Understanding the Biochemical Driving Forces and Redox Reactions. Acc. Chem. Res. 2019, 52 (6), 15071518.


 承担科研项目情况:
 

1.作为项目首席科学家承担政府间国际科技创新合作重点专项1项;

2.作为课题负责人承担国家重点研发计划大装置前沿研究专项课题1项;

3.作为项目负责人承担国家自然基金委面上项目1项;

4.作为项目负责人承担国家自然基金委青年基金项目1项;

5.作为课题负责人承担国家自然基金委重点项目1项;

6.作为主要参与人,参加了国家自然科学基金重大仪器研制、重大、面上等10项研究项目以及973项目3项,先导B项目1项。